疑难病杂志Issue(9)：881-883,3.DOI:10.3969/j.issn.1671-6450.2014.09.001
血浆纤维蛋白原与冠状动脉病变的关系研究
Study on the relationship between coronary artery lesions an d plasma fibrinogen
摘要
Abstract
Objectvi e To investigate the relationship between coronary artery lesions and plasma fibrinogen (Fg). Methods From 2014 February to April , 91 cases of patients with suspected stable coronary artery disease were enrolled , based on the admission of basic clinical data , according to the results of coronary angiography , they were divided into non-cor-onary artery disease group of 21 cases, single vessel disease group of 37 cases, 2 lesions in 16 cases, 3 vessel or left main le-sion group in 17 cases.Fg, total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL -C) were detected .Analyzed the relationship between plasma fibrinogen and coronary ar-tery disease.Results Compared with non-coronary artery disease group ,2-vessel group and 3-vessel or left main lesion group ’ s Fg levels were elevated,the differences were significant ( P<0 .05).Multivariate Logistic regression analysis showed:gen-der (OR=9.72, 95%CI 1.56-60.76, P =0.02), age (OR=1.09, 95%CI 1.00-1.17,P =0.04), TC (OR=10.87, 95%CI 1.56-762.4 , P =0.02), LDL-C (OR=1.06, 95%CI 1.01-1.50, P=0 .01), Fg (OR=74.0 ,95 %CI 1.82-30.03, P =0.01)were risk factors for coronary artery disease .Conclusion Gender, age, TC, LDL-C, Fg are risk factors for coronary artery disease , Fg level was increased in coronary artery disease patients , but the relationship with the severity of dis-ease is not determined yet .关键词
纤维蛋白原/冠状动脉病变/关系Key words
Fibrinogen/Coronary artery lesion/Relationship引用本文复制引用
王欣,夏豪,童随阳,李磊..血浆纤维蛋白原与冠状动脉病变的关系研究[J].疑难病杂志,2014,(9):881-883,3.基金项目
2012年国家自然科学基金资助 （）
