摘要
Abstract
Objective To investigate the clinical manifestations and imaging characteristics of neonatal hypoglycemic brain injury.Methods From July 2011 to June 2013, retrospectively analyzed clinical data of 62 cases of hospitalized neo-natal hypoglycemia , according to brain injury , they were divided into brain injury group of 30 cases and non-brain injury group of 32 cases, compared the 2 groups’ first treatment time, open milk time and blood glucose etc .Results The difference of the 2 groups’ birth weight, gestational age, the first diagnosis of hypoglycemia time revealed no significant ( P >0.05);brain injury group’s minimum average blood glucose value lower than that without brain injury group [(1.3 ±0.4) mmol/L vs.(1.6 ±0.3) mmol/L, t =3.507, P <0.01], hypoglycemia lasts longer than without brain injury group [(28.4 ±11.2) h vs.(6.0 ±2.5) h, t =10.711, P <0.01], delayed feeding time longer than without brain injury group [(1.8 ±0.4) h vs.(0.8 ±0.2) h, t =12.445, P <0.01].The most common clinical manifestations of neonatal hypoglycemic brain injury were convulsion , milk refusal and the indifference response .Brain MR or CT brain image characteristics revealed that the most common involvement areas are occipital and parietal lobe .Follow up was 6 months, brain injury group have sequela of nervous system in 9 cases, and no case in non-brain injury group.Conclusion For neonates with high risk factors , early blood glu-cose monitoring , timely intervention is necessary to prevent the occurrence of hypoglycemic brain injury .Cranial MR and brain CT revealed the occipital and parietal lobe involvement is helpful for diagnosis of hypoglycemic brain injury .关键词
新生儿/低血糖/脑损伤Key words
Neonatal/Hypoglycemia/Brain injury
