摘要
Abstract
Objective To investigate the efficiency and safety of interventional therapy for treatment of malformation in congenital heart disease ( CHD) .Methods There were 19 cases of CHD complex malformation, male was 11 cases, fe-male was 8 cases, age ranged from 5 to 36 (15.2 ±10.7) years old, body weight ranged from 25.6 to 55.8 (32.2 ±26.1) kg;CHD including atrial septal defect ( ASD) combined with patent ductus arteriosus ( PDA) in 5 cases, ASD with pulmona-ry valve stenosis ( PS) in 6 cases, ASD with ventricular septal defect ( VSD) in 3 cases, 3 cases of VSD complicated with PS, 1 cases of PDA complicated with PS, 1 cases of PDA with type B pre-excitation syndrome.Interventional therapy in the order of:PS balloon dilation, VSD closure, PDA closure, ASD closure; PDA with pre-excitation syndrome was first with radiofre-quencyablationtherapy,thenforPDAclosure.Results 19patientswerereceived1timesuccessfulinterventionaltreatment, no serious complications occurred during the operation, postoperative angiography and cardiac ultrasound demonstrated no ob-vious residual shunt were occurred, and the occluder fixed well.In 10 cases of patients with PS, the systolic pressure across pulmonary valve were decreased from (50.6 ±17.2) mm Hg preoperative to (21.2 ±9.5) mm Hg postoperative ( t =6.28, P <0.01).In 14 cases of ASD patients complicated with other malformations, all of them received ASD occluder therapy, occluder diameter with averaged of (20.6 ±10.5) mm;in 6 cases of PDA patients complicated with other malformations, 2 cases received coil occlusion, the other 4 patients received with PDA septal occluder, average diameter of (7.1 ±2.5) mm;VSD combined with other deformities in 6 cases, 4 cases in the membranous, and combined with membranous aneurysm for-mation in 2 cases, all of them received the symmetric VSD closure, the occluder diameter with averaged of (9.5 ±3.2) mm. Conclusion Strict indications with reasonable operation strategy, the interventional treatment of CHD complex malformation revealed curative effects with safety and feasible.关键词
心脏缺损,先天性/心脏导管插入术/复合畸形/介入治疗Key words
Heart defect,congenital/Cardiac catheterization/Multiple malformation/Interventional therapy
