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复发性翼状胬肉切除术联合丝裂霉素与自体角膜缘干细胞移植的疗效观察

李化

医学信息Issue(13):120-120,1.
医学信息Issue(13):120-120,1.

复发性翼状胬肉切除术联合丝裂霉素与自体角膜缘干细胞移植的疗效观察

To Observe the Curative Effect of Recurrent Pterygium Excision Combined with Mitomycin C and Autologous Corneal Limbal Stem Cell Transplantation

李化1

作者信息

  • 1. 贵州省人民医院眼科,贵州贵阳 550000
  • 折叠

摘要

Abstract

Objective To compare the curative ef ect of limbal epithelial autografi and recurrent pterygium excision with mitomycin C in treatment of recurrent pteryghim. Methods A total of 78 patients (94 eyes)with recurrent pterygium were randomly divided into two groups:Group A 43 cases (52 eyes)was performed resection of pterygium plus mitomycin C;Group B 35 cases (42 eyes)Was performed autologous limbus stem celltransplantation after pteryguim excision.The curative ef ect Was evaluated according to criteria Prabhasawat advanced after average 15 months of postoperative fol ow-up including cure rate.Results The cure rate of pterygium in Group B(92.86%)Was higher than thai in Group A(78.84%),the dif erence between the two groups Was significant( P<0.05).Conclusion Autologous limbus stem celltransplantation conducing to reconstructing limbal barrier function is more ef ective in treatment of recurrent pterygium with high cure rate.Low recurrence rete and much improvement of astignatism.

关键词

复发性翼状胬肉/自体角膜缘干细胞移植/角膜/丝裂霉素C

Key words

Recurrent pterygium/Autologous limbus stem celltransplantation/Cornea/Mitomycin C

引用本文复制引用

李化..复发性翼状胬肉切除术联合丝裂霉素与自体角膜缘干细胞移植的疗效观察[J].医学信息,2014,(13):120-120,1.

医学信息

1006-1959

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