医学信息Issue(13)：185-186,2.
以FreeSurfer活体测量屈光参差性弱视枕叶皮质形态学改变的MRI研究
MRI Study on Gray Matter Volume Change in Occipital Lobe in Vivo of Anisometropic Amblyopia with FreeSurfer
周扬 1姜召福 1鲁冰 1孔丽丽 1陈玉飞 1王玉东 1王金财 1崔巍 1赵洪全1
作者信息
- 1. 烟台经济技术开发区医院影像科，山东 烟台 264006
- 折叠
摘要
Abstract
Objective Using MRI (Magnetic resonance imaging) technique and the FreeSurfer software package to research the occipital lobe's gray mat er volume (GMV) change in children with Anisometropic amblyopia. Methods 11 normal sighted children and 11 children with Anisometropic amblyopia undertook MRI scans. The two groups were age-matched. Standard T1-weighted high-resolution anatomic scans with 3D-MPRAGE (three dimensional magnetization prepared rapid acquisition gradient echo) sequences were obtained for each subject.The 3-demension data were analyzed using FreeSurfer software . After inflated the brain cortex of the patients and normal groups , gray mat er volume in bilateral occipital lobe and ICV (the estimate total intracranial volume)were calculated. The statistic analyses of the data between the two groups were performed with the student t test. Results The patients of Anisometropic amblyopia showed a significant decrease in gray mat er volume compared with healthy controls:t=2.618,P=0.016;t=2.515,P=0.021 ( P<0.05). Conclusion Our results suggest that gray mat er volume is smal er in patients of anisometropic amblyopia compared with healthy controls;Through FreeSurfer analysis, we could observe the morphological variation of the occipital lobe without invasive.关键词
屈光参差性弱视/灰质容积/磁共振成像/FreeSurferKey words
Anisometropic amblyopia/Gray mat er volume/MRI/FreeSurfer引用本文复制引用
周扬,姜召福,鲁冰,孔丽丽,陈玉飞,王玉东,王金财,崔巍,赵洪全..以FreeSurfer活体测量屈光参差性弱视枕叶皮质形态学改变的MRI研究[J].医学信息,2014,(13):185-186,2.
