摘要
Abstract
Objective Clinical analysis of 73 cases of drug-induced liver disease. Methods 75 cases of drug-induced liver disease patients in our hospital from 2010 November to 2013 November were carried on clinical analysis. Results 29 cases (39.73%) patients with liver damage occurred in the medication after more than 8 weeks, 14 cases (19.19%) occurred in 4~8 weeks after treatment, 24 cases (32.88%) occurred at 1~4 weeks after treatment, 6 cases (8.22%) occurred at 1 weeks after treatment. In 11 cases (15.07%) were greater than 6%eosinophils, 65 cases (89.04%) of the patients with abnormal bilirubin, 68 cases (93.15%) the elevation of AST, 70 cases (95.89%) increased ALT. The group of 1 patients (1.37%) patients died, 14 cases (19.18%) transferred or discharged, 58 cases (79.45%) improved or cured. Conclusion The treatment of drug-induced liver disease prevention, as far as possible not to use for the human liver toxic drugs, nor a large number of long-term medication or drug abuse.关键词
药物毒性/临床表现/药物性肝病Key words
Drug toxicity/Clinical manifestation/Drug-induced liver disease