摘要
Abstract
Objective To review the progress of improving the homing ability of BMMSCs in the distal way by cytokines,traditional Chinese medicine and bi-antibody, provide a theoretical basis for the study of BMMSCs homing.Methods Documents in the PubMed,wanfang databases and VIP databases from January 2002 to January 2013 were searched by computer using key words of"stem cells,myocardial infarction,home"both in English and Chinese Papers related to myocardial infaction,distal way,homing,revascularization of myocardial tissue.Results With the help of cytokine,traditional Chinese medicines and bi-antibody,transplantated mesenchymal stem cells can home ef ectively for the treatment of myocardial infarction.Via the subcutaneous ,vein, body cavity, in vitro pretreatment,the ef ect infactors express relatively safe, convenient way to improve stem cellhoming rate without coronary or cardiac puncture risks.Conclusion But this technology is not mature with many problems to be solved. The mechanism of various ways for the improvement of heart function and influence needs further study.关键词
心肌梗死/骨髓间充质干细胞/归巢Key words
Myocardial infarction/Bone marrow mesenchymal stem cells/BMMSCs/Homing
