摘要
Abstract
Objective To compare high-dose omeprazole and routine dose of omeprazole in the treatment of ulcerative upper digestive tract hemorrhage treatment ef ect. Methods 156 patients were randomly divided into treatment group and control group with 78 cases in each. Treatment group:first given omeprazole 80mg join saline 20ml slow intravenous injection, about 5~10 minutes to finish, and then omeprazole 80mg join saline 50ml adding trace pump continuous infusion, with the speed of 8mg/h, continuous infusion of 72 hours; the control group: Omeprazole 40mg join saline 100ml, at a frequency of q12h intravenous drug use, 72 hours. The two groups were observed and compared hemostatic efficiency, rebleeding rate, transmission and suspension of red blood cells, adverse reaction. Results The total ef ective rate ( <0.05):treatment group 94.8%, control group total ef ectiveness is 80.7%;. 72 re bleeding rate in H ( <0.05): treatment group 1.28%, control group 6.41%; the average cases of red blood celltransfusion suspension input ( <0.05): the treatment group (2 ± 1) U, the control group (4 ± 1.1) U; two groups were no obvious adverse reactions. Conclusion Large dose of omeprazole group on the hemostatic effect is bet er than conventional dose of omeprazole group of acute upper digestive tract bleeding ulcer, no significant adverse reactions, and can shorten the time of hospitalization, hospitalization cost saving, worthy of further application in basic hospital.关键词
奥美拉唑/治疗/溃疡性上消化道出血Key words
Omeprazole/Treatment/Gastrointestinal hemorrhage of upper digestive ulcer
