摘要
Abstract
Objective To study the relationship between chronic left ventricular dysfunction and TNF, IL-1 and IL-6. Methods 60 cases of chronic left ventricular dysfunction patients admit ed in the Cardiology Department of our hospital from Aug. 2009 to Feb. 2012 were chosen as the observation group. 60 healthy persons who did the physical examination in our hospital in the same period were chosen as control group. The content of TNF-α, IL-1 and IL-6 in their serum were tested. Results The content of TNF-α, IL-1 and IL-6 in observation group were apparently higher than control group, and the dif erence was statistical y significant (P<0.05). The content of TNF-α, IL-1 and IL-6 increased with the elevation of cardiac function classification level, and the dif erence between each team was statistical y significant (P<0.05). Conclusion The level of TNF-α, IL-1 and IL-6 in chronic left ventricular dysfunction patients were markedly elevated, and it increased with the elevation of cardiac function classification level, which is positive correlation.关键词
慢性左心功能不全/TNF-α/IL-1/IL-6Key words
Chronic left ventricular dysfunction/TNF-α/IL-1/IL-6