摘要
Abstract
Objective 99 infants of grow delaying or facial deformity in this hospital have been analyzed by peripheral blood cel s cultivation ,so as to provide genetic test evidences for clinical diagnosis. Methods Peripheral blood cel s cultivation, medical slice, G banding, resistance type analysis.Results Among the 99 infants, 57 cases have abnormal chromosome, the detection rate is 57.6%. And of the 57 cases, 55 cases are trisomg 21-syndrome, accounting for 96.5%.Conclusion Trisomg 21-syndrome is the main cause of\ children's grow delaying or mental deficiency , special check of the peripheral blood cel s chromosome and prenatal diagnosis for pregnant woman are critical methods to reduce the birth of defective babies.Trisomg 21-syndrome, or named inborn slow-wit ed, is the common and the first diagnosed blood cel s chromosome disease for our human beings. In 1866, England doctor Lang-don Down published clinical survey about this disease, then it named Down Syndrome in external, named TangShi Syndrome in internal. In 1959, the franco-doctor Lejeune diagnosed inborn slow-wit ed patient's cel have another 21 chromosome, then named this disease Trisomg 21-syndrome.关键词
先天愚型/核型分析Key words
Trisomg 21-syndrome/Karyotype analysis
