摘要
Abstract
Objective Not explicitly discuss the diagnosis of atypical squamous cells of clinical treatment, to provide reference for clinical treatment Test program. Methods The hospital in February 2009~2014 February clinic liquid-based cervical cytology is not explicitly confirmed the diagnosis of atypical squamous cells of 345 patients as observed objects were randomly divided into A, B, c three groups: group A 124 patients after three months again, liquid-based cervical cytology; 113 patients in group B after liquid-based cervical cytology finished joint inspection of high-risk human papil omavirus; 108 patients in Group C joint colposcopy and cervical biopsy after liquid-based cytology is completed. Inspection of the three groups of patients with atypical squamous epithelial cells of cervical intraepithelial neoplasia.Results Group A cytological abnormality detection rate of 54.05%of CIN, cytology normal CIN detection rate 6.89%, the dif erence was statistical y significant (χ²=8.81,P<0.05);B HPV-positive detection rate in CIN to 43.90%, HPV-negative not check out CIN; 108 patients in Group C direct colposcopy and biopsy detection rate of 29.63% CIN;invasive cervical cancer was not found; Group A method for predicting cervical high-grade lesions in ASCUS (CIN≥aboveII) sensitivity of 73.9% and a specificity of 72.8% and a negative predictive value of 97.7%, a positive predictive value of 26.4%, the proportion of Group B were 100.0%, 65.8%, 100.0%, 26.7%, by ROC analysis of the two methods to predict the inflection point was no significant dif erence (P>0.05) in patients with cervical ASCUS accuracy of high-level lesions. Conclusion High-risk groups or people in need of poor compliance or colposcopic biopsy to detect high-risk HPV, and make personalized management of patients with ASCUS.关键词
不典型鳞状上皮细胞/人乳头瘤病毒/液基细胞学检查Key words
Atypical squamous cells/Human papil omavirus/Liquid-based cytology
