医学信息Issue(23):118-118,1.
盐酸戊乙奎醚对体外循环患者肝功能的影响
Effects of Penehyclidine Hydrochloride on Liver Injury Induced by Cardiopulmonary Bypass
摘要
Abstract
Objective To investigate the ef ects of penehyclidine hydrochloride on liver injury induced by cardiopulmonary bypass (CPB). Methods Forty patients undergoing valve replacement with CPB were randomly divided into two groups(n=20):group PHC and group C. Pnehyclidine hydrochloride 0.1mg/kg was injected intravenously before 5min CPB.Blood samples were col ected for AST,ALT,DB,SB and TB before CPB (T0),after 5min aorta block(T1),CPB cease(T2)and after 48h operation (T3).Results The levels of AST,ALT,DB,SB and TB in group PHC were significantly lower at T1~T3 than those in group C( <0.05). Conclusion Penehyclidine hydrochloride can reduce liver injury induced by CPB.关键词
盐酸戊乙奎醚/体外循环/肝脏损害Key words
Penehyclidine hydrochloride/Cardiopulmonary Bypass/Liver injury引用本文复制引用
胡彦艳,黄爱兰,卢小玲,叶凤青,朱蔚琳,黄中华,马利..盐酸戊乙奎醚对体外循环患者肝功能的影响[J].医学信息,2014,(23):118-118,1.基金项目
广西医疗卫生厅重点科研课题,合同编号桂卫重2012144 ()