摘要
Abstract
Objective To compare three methods for detection of syphilis, improve the clinical diagnosis of syphilis.Methods A total of 8178 cases of syphilis including outpatients and inpatients were col ected from 2012 October to 2013 October, among which 200 serum samples selected by TP-ELISA were detected by TPPA and TRUST methods, the TPPA results as confirmation. Results Can be obtained with the standard of TPPA that the sensitivity of TP-ELISA was higher and TRUST was lower, the dif erence was statistical y significant (P<0.05). Conclusion Specificity of the two methods was high, no significant dif erence ( P>0.05). TP-ELISA method is suitable for large-scale clinical screening and diagnosis, the TRUST method is not suitable for mass screening because of the lower sensitivity, in order to improve the detection rate and accuracy of syphilis, we advice examing and confirming by TPPA. Three kinds of detection methods combined application can more ef ectively improve the rates of clinical diagnosis.关键词
梅毒/酶联免疫吸附试验/梅毒螺旋体明胶颗粒凝集试验/甲苯胺红不加热血清试验Key words
Syphilis/Enzyme-linked immunosorbent assay/Treponema pallidum gelatin particle agglutination test for syphilis/Methylaminered unheated serum test