摘要
Abstract
Objective To observe the thalidomide and chemotherapy ef icacy of vascular endothelialgrowth factor(VEGF) and tumor necrosis factor(TNF-a) in the serum of advanced non-smal cell lung cancer. Methods 40 cases of advanced non-smal celllung cancer were randomly divided into groups of thalidomide and GP chemotherapy (treatment group) and GP chemotherapy (control group). Clinical observation on treatment of 4 cycles . content by ELISA method for detection of VEGF and TNF-a before and after treatment in peripheral serum. Results The remission rate in the treatment group was 65%, control group 55%, There was no significant dif erence between two groups, but two groups had no statistical difference, but the content of serum VEGF and TNF-a decreased significantly ( <0.05). Conclusion Thalidomide and chemotherapy can significantly reduce VEGF and TNF-a in serum of patients with advanced lung cancer level.关键词
晚期非小细胞肺癌/沙利度胺/VEGF/TNF-aKey words
Advanced non-smal celllung cancer/Thalidomide/VEGF/TNF-a
