摘要
Abstract
Objective To compare the ef ects of propofol and sevoflurane on early cognitive function for elderly patients. Methods 62 patients over the age of 65, ASA Ⅰ~II, and thoracic and abdominal operation were screened, they were divided into propofol group and sevoflurane group, each group had 31 cases. Pre-and postoperative in 6 h, 12 h, 24h and 48h conditions of patients as wel as MMSE were rated. Results Patients were used propofol and sevoflurane with 6h, 12h, 24h hours ,Their MMSE score had significant dif erence ( <0.05), and with the extension of time, POCD could be improved and got back to normal after 48h.Conclusion Propofol and sevoflurane could reduce the early cognitive function for elderly patients, but cognitive function recovered more quickly for sevoflurane than propofol.关键词
丙泊酚/七氟醚/术后认知功能障碍Key words
Propofol/Sevoflurane/Postoperative cognitive dysfunction