医学信息Issue(34)：144-144,145,2.
降钙素原检测在新生儿败血症早期诊断中的应用
Clinical Analysis of Procalcitonin Detection in Early Diagnosis of Neonatal Sepsis
陆银宝1
作者信息
- 1. 淮安市妇幼保健院，江苏 淮安 223002
- 折叠
摘要
Abstract
Objective To investigate Procalcitonin (PCT) for early diagnosis of neonatal septicemia. Methods The serum PCT levels were measured with immune chromatography (PCT-Q)assay and compared with the serum C-reactive protein (CRP)in 84 neonates of whom were divided into neonatal septicemia group, common infection group and non-infection group according to discharge diagnosis. Results Serum concentrations of PCT and CRP in neonatal septicemia group were significantly higher than those common group and non-infection group ( <0.05). Serum concentrations of PCT and CRP in neonates with common infection were significantly higher than those non-infection ( < 0.05). Set 0.5ng/ml as cut-of value, PCT was positive in 93.3% neonatal septicemia, the specificity rate was 80.8%. Set 8.0ng/ml as cut-of value, CRP was positive in 70.0%neonatal septicemia, the specificity rate was 69.2%. The sensitivity and specificity rate of PCT were much higher than that of CRP. The level of the serum PCT decreased rapidly during ef ective antibiotic therapy. Conclusion The measurement of PCT wil be very important to the early and dif erential diagnosis and judgment of therapeutic ef icacy of neonatal infection.关键词
降钙素原/C反应蛋白/新生儿/败血症/诊断Key words
Procalcitonin/C-reactive protein/Neonatal/Septicemia/Diagnose引用本文复制引用
陆银宝..降钙素原检测在新生儿败血症早期诊断中的应用[J].医学信息,2014,(34):144-144,145,2.
