摘要
Abstract
Objective A comparative analysis of propylthiouracil and methimazole treatment of hyperthyroidism ef icacy and safety. Methods In our hospital were randomly 60 patients with hyperthyroidism group, divided into experimental and control groups, 30 cases in each. Test group:the introduction of sulfide azole microphone (MMI) medication. Control group:the introduction of propylthiouracil (PTU) medication. Results Compared to the experimental group and the control group, the adverse reaction of methimazole drugs, such as neutropenia, rash rate significantly higher than the control group, there were statistical y significant ( <0.05);adverse reaction of propylthiouracil drugs, such as the incidence of toxic liver disease was significantly higher than that in experiment group, there were statistical y significant ( <0.05).Conclusion Using methimazole treatment of hyperthyroidism, can lead to neutropenia, rash and other adverse reactions. When using propylthiouracil therapy for hyperthyroidism, can lead to liver toxicity and other adverse reactions.关键词
甲巯咪唑/丙硫氧嘧啶/甲亢Key words
Methimazole/Methylthio al oxan/Hyperthyroidism
