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胃肠道间质瘤靶向治疗的耐药机制及治疗策略

周飞(综述) 朱家胜(审校)

医学信息Issue(9):349-349,350,2.
医学信息Issue(9):349-349,350,2.

胃肠道间质瘤靶向治疗的耐药机制及治疗策略

Resistance Mechanism and Treatment Strategy of Gastrointestinal Stromal Tumor Target Therapy

周飞(综述) 1朱家胜(审校)1

作者信息

  • 1. 皖南医学院附属弋矶山医院胃肠外科一病区,安徽 芜湖 241000
  • 折叠

摘要

Abstract

Gastrointestinal stromal tumor (GIST) is the most common gastrointestinal mesenchymal tumors. Nowadays, imatinib mesylate is a smal molecule targeted drugs such as ef ective in the treatment of GIST in clinical, but some patients stil suf ered from primary or secondary resistance. The resistance to GIST is due to the dif erent types of gene mutation. Therefore, we should be based on the genetic types and tumors specific circumstances to provide individualized treatment in clinical work, so that not only can improve the therapeutic ef ect, but also can improve the quality of life.

关键词

胃肠间质瘤/靶向治疗/耐药/治疗策略

Key words

Gastrointestinal stromal tumors/Targeted therapy/Drug resistance/Treatment strategy

引用本文复制引用

周飞(综述),朱家胜(审校)..胃肠道间质瘤靶向治疗的耐药机制及治疗策略[J].医学信息,2015,(9):349-349,350,2.

医学信息

1006-1959

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