医学信息Issue(14)：53-53,1.
IL-10在系统性红斑狼疮患者血清中的表达及意义
Expression and Significance of IL-10 in Serum of Patients with Systemic Lupus Erythematosus
朱强 1朱明华 1何敬之 1王旭彦 1罗俊 1王浩 1刘华1
作者信息
- 1. 华北石油总医院肾内科，河北 任丘 062552
- 折叠
摘要
Abstract
Objective To investigate the serum levels of IL-10 and their significance in patients with Systemic Lupus Erythematosus (SLE).Methods A total of 135 cases were available for the study including 63 cases of primary group, 40 cases of remission group and 32 cases of healthy control group.ELISA method was used to determine the concentrations of IL-10 in serum.Results The levels of IL-10 in serum of primary group were significantly higher than that of remission group and healthy control group. The levels of IL-10 in serum of remission group were significantly higher than that of healthy control group( <0.05). 63 cases of primary group were divided into three groups by SLEDAI:21 cases in mild activities group, 30 cases in moderate activities group,12 cases in severe activities group, the levels of IL-10 among the three groups were significant dif erence ( <0.05). The levels of IL-10 in primary group had active cor elation with SLEDAI. Conclusion IL-10 is involved in the immune damage process and associated with activity and severity in patients with SLE.关键词
红斑狼疮/细胞因子/白细胞介素10Key words
Lupus erythematosus/Cytokines/Interleukin-10引用本文复制引用
朱强,朱明华,何敬之,王旭彦,罗俊,王浩,刘华..IL-10在系统性红斑狼疮患者血清中的表达及意义[J].医学信息,2015,(14):53-53,1.
