医学信息Issue(16)：18-19,20,3.
急性白血病合并真菌感染临床特点及预后相关因素分析
Clinical Characteristics and Analysis of Prognostic Factors of Acute Leukemia Complicated with Fungal Infection
郑永青1
作者信息
- 1. 滨州医学院附属滨州市市人民医院血液科，山东 滨州 256610
- 折叠
摘要
Abstract
Objective To investigate the clinical characteristics and prognosis fungal Infection in patients with acute leukemia. Methods The cases of fungal infection in acute leukemia patients ,between 2007 /8 and 2014/05,were col ected retrospectively from hematology department of binzhou people Hospital. The factors which influence the prognostic factors to be investigated .Chi-square test and Logistic regression analysis were used for statistics. Results The incidence of fungal infection in acute leukemia was 27.54%,and mortality rate was 11.46%.The frequently presented fungus was the saccharomyces(84.15%),then mould(10.98%).The common site of infection is the respiratory tract(64.63%)、intestinal tract(23.13%),oral cavity(8.84%),According to multivariate Logistic regression analysis, only age、the duration of neutropenia≥2weeks,history of fungus infection multiple organ failure are the the factors associated with the curative ef ect of fungal infections( <0.05).The duration of neutropenia≥2weeks,history of fungus infection multiple organ failure are the the factors associated with the mortality of fungal infections ( <0.05).Conclusion The common site of fungal infection is the respiratory tract intestinal tract oral cavity;The frequently presented fungus was the saccharomyces,age≥60、the duration of neutropenia ≥2weeks history of fungus infection multiple organ failure are the the factors associated with the curative ef ect of fungal infections.The duration of neutropenia ≥2weeks、history of fungus infection、multiple organ failure are the the factors associated with the mortality of fungal infections.关键词
急性白血病/真菌感染/预后影响因素/Logistic回归Key words
Acute leukemia/Fungal infection/Prognostic factors/Logistic regression analysis引用本文复制引用
郑永青..急性白血病合并真菌感染临床特点及预后相关因素分析[J].医学信息,2015,(16):18-19,20,3.
