摘要
Abstract
Objective To analyze the distribution and drug resistance of nosocomial infection of pathogenic,and provide the basis for rational use of antimicrobial drugs to control and prevent nosocomial infections.Methods A retrospective analysis of 260 cases of nosocomial infection patients from 2011 to 2013 in our hospital,clinical data was analyzed to find the distribution of pathogens and their drug resistance.Results 260 cases of nosocomial infections were detected in 438 patients with pathogens,including gram-positive bacteria 124 (28.31%)and Staphylococcus aureus glucose was the majority, gram-negative bacteria 232 (52.97%),and Escherichia bacteria,Pseudomonas aeruginosa were the majority,fungi 82 (18.72%),mainly to Candida tropicalis;Gram-positive bacteria had strong resistance to penicil in,levofloxacin,clindamycin,erythromycin and Gram-negative bacteria had strong resistance to third-generation cephalosporins,fluoroquinolones and aminoglycosides while fungal had low resistance to antimicrobial drugs.Conclusion The nosocomial infection pathogens are mainly Gram-negative bacteria which has strong resistance.Therefore,in clinic reasonable and ef ective dosing regimen should be developed based on the distribution of nosocomial infection pathogens and drug resistance analysis,thereby enhancing antimicrobial drugs role in reducing the generation and spread of resistant bacteria,which is important for the control of nosocomial infection.关键词
内感染/病原微生物/分布/耐药性Key words
Nosocomial infection/Pathogenic microorganism/Distribution/Drug resistance
