医药导报Issue(6)：721-722,2.DOI:10.3870/yydb.2014.06.007
牛大力水提物和醇提物急性毒性实验研究
Acute Toxicity Study of Water and Ethanol Extracts of Radix Millettiae Speciosae
摘要
Abstract
Methods The maximum tolerated dose( MTD)of water and ethanol extracts of Radix millettiae speciosae were measured for the safety evaluation. Results Maximal tolerated dose( MTD)of water extract was higher than 1 000 g·kg-1 ,which equaled to 110 times the dose for human adults(60 kg). MTD of ethanol extract was higher than 1 700 g·kg-1 ,which equaled to 186 times the dose for human adults(60 kg). Conclusion Radix millettiae speciosae does not have obvious toxicity,thus its routine clinical dose is safe and feasible.关键词
牛大力水提物/牛大力醇提物/毒性实验,急性/最大耐受量Key words
Water extract of Radix millettiae speciosae/Ethanol extract of Radix millettiae speciosae/Toxicity experiment,acute/Maximum tolerated dose分类
医药卫生引用本文复制引用
杨增艳,周海松,赵湘培,唐瑾,柏春晖..牛大力水提物和醇提物急性毒性实验研究[J].医药导报,2014,(6):721-722,2.基金项目
2012年度广西壮族自治区卫生厅中医药科技专项课题 （）
