医药导报Issue(8)：1080-1082,3.DOI:10.3870/yydb.2014.08.028
单因素实验结合响应面法优化朱砂根总皂苷的提取工艺
Optimization of Extraction Technology for Total Saponins of Ardisia Crenata by Singlefactor Experiment Combined with Response Surface Methodology
吴琴 1陈珣2
作者信息
- 1. 贵州理工学院制药工程学院，贵阳 550003
- 2. 毕节学院化学工程学院，毕节 551700
- 折叠
摘要
Abstract
Objective To optimize the extraction process of Ardisia crenata based on the content of total saponins and to provide a basis for the Ardisia crenata study. Methods Based on the results of the single-factor tests and the Box-Behnken central composite experimental design principles, a response surface methodology which has three factors and three levels was designed to optimize the extraction process of Ardisia crenata based on the content of saponins. Results A maximal extraction yield of total saponins reached 2. 29% under the optimal conditions as follows:70% alcohol was used as extraction solvent with the material to liquid ratio of 116, the extraction time was 3 h at 70 ℃. Conclusion The optimized extraction process is accurate, reliable and practically valuable.关键词
朱砂根/总皂苷/响应面法/提取工艺Key words
Ardisia crenata/Total saponins/Response surface methodology/Optimization of extraction分类
医药卫生引用本文复制引用
吴琴,陈珣..单因素实验结合响应面法优化朱砂根总皂苷的提取工艺[J].医药导报,2014,(8):1080-1082,3.
