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碳及碳团簇负离子注入硅橡胶细胞相容性研究

郑晨龙 徐亚 仇猛淋 庞学雯 吴正龙 王广甫

原子能科学技术Issue(7):1309-1314,6.
原子能科学技术Issue(7):1309-1314,6.DOI:10.7538/yzk.2015.49.07.1309

碳及碳团簇负离子注入硅橡胶细胞相容性研究

Cell Biocompatibility Study of Silicon Rubber by Carbon and Cluster Carbon Negative Ion Implantation

郑晨龙 1徐亚 1仇猛淋 1庞学雯 2吴正龙 3王广甫1

作者信息

  • 1. 北京师范大学核科学与技术学院射线束技术与材料改性教育部重点实验室,北京 100875
  • 2. 北京大学医学部基础医学院免疫学系,北京 100191
  • 3. 北京师范大学分析测试中心,北京 100875
  • 折叠

摘要

Abstract

A negative cluster ion implantation system with “Charge‐up free”characteris‐tic was established by installing a sample holder and an electrostatic scanner on the in‐jector of the GIC4117 tandem accelerator .The carbon and cluster carbon negative ion implantation was used for surface modification study of cell biocompatibility of silicon rubber (SR) .The measure of water contact angle shows ,with an increase in dose up to 3 × 1015 cm -2 ,the water contact angle decreases from about 108.7° to 103.1° and the surface hydrophilicity is promoted .The XPS results indicate ,with an increase in dose , the surface composition of carbon atoms decreases w hile oxygen and nitrogen atoms fraction increases .Based on above results ,the mechanism of negative ion implantation cell biocompatibility modification of SR was discussed .Finally ,cells were cultured on the sample , and the result show s that negative ion implantation is a convenient and effective method to improve cell biocompatibility of SR .

关键词

负离子注入/硅橡胶/表面改性/XPS/细胞相容性

Key words

negative ion implantation/silicon rubber/surface modification/XPS/cell biocompatibility

分类

能源科技

引用本文复制引用

郑晨龙,徐亚,仇猛淋,庞学雯,吴正龙,王广甫..碳及碳团簇负离子注入硅橡胶细胞相容性研究[J].原子能科学技术,2015,(7):1309-1314,6.

基金项目

北京市自然科学基金资助项目 ()

原子能科学技术

OA北大核心CSCDCSTPCD

1000-6931

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