中国病理生理杂志Issue(7)：1218-1222,1227,6.DOI:10.3969/j.issn.1000-4718.2014.07.012
重编程诱导多功能干细胞的研究进展
Research progress in reprogramming induced pluripotent stem cells
摘要
Abstract
Induced pluripotent stem cells ( iPSCs) have been first induced from mouse fibroblasts since 2006, and the research on iPSCs has made great progress in the following years .iPS cell lines were established from different so-matic cells through DNA , RNA, protein, and small molecule compounds and various methods of transduction , making the induction of iPSCs more secure and effective , and more attractive prospect of clinical application .In this review , different somatic cell reprogramming , different levels of reprogramming , different transduction pathways , and prospect of application are discussed .关键词
诱导多能性干细胞/安全性/有效性Key words
Induced pluripotent stem cells/Safety/Efficiency分类
医药卫生引用本文复制引用
郭晓令,刘庆,王婵,郭永龙,余榕捷,陈建苏..重编程诱导多功能干细胞的研究进展[J].中国病理生理杂志,2014,(7):1218-1222,1227,6.基金项目
国家自然科学基金资助项目（No．81371689）；广东省自然科学基金资助项目 （）
