中国当代儿科杂志Issue(10)：1001-1004,4.DOI:10.7499/j.issn.1008-8830.2014.10.009
肺炎支原体肺炎患儿血清TNF-α、IL-6及半乳凝素3浓度测定的临床意义
Serum tumor necrosis factor-α, interleukin -6 and galctin-3 concentrations in children with Mycoplasma pneumoniae pneumonia
田芳 1韩波 2段梅3
作者信息
- 1. 山东淄博市妇幼保健院儿科，山东淄博 255000
- 2. 山东省省立医院儿科，山东济南 250021
- 3. 山东淄博矿业集团中心医院检验科，山东淄博 255120
- 折叠
摘要
Abstract
Objective To study the changes in serum tumor necrosis factor-α(TNF-α), interleukin-6 (IL-6) and galctin-3 (Gal-3) concentrations in children with Mycoplasma pneumoniae pneumonia (MPP), and their roles in MPP. Methods Serum TNF-α, IL-6 and Gal-3 concentrations were measured using double antibody sandwich ELISA in 48 children with acute MPP (severe:21 cases;mild:27 cases) and in 30 healthy children (control group). Results Serum concentrations of TNF-α, IL-6 and Gal-3 in both the severe and mild groups were significantly higher than in the control group before treatment. The concentrations of the three indexes in the severe group were signiifcantly higher than in the mild group. Serum concentrations of the three indexes decreased signiifcantly after treatment in both groups. Conclusions Serum TNF-α, IL-6 and Gal-3 play important roles in the occurrence and development of pediatric MPP and their levels are associated the severity of this disorder.关键词
肺炎支原体肺炎/肿瘤坏死因子-α/白细胞介素-6/半乳凝素-3/儿童Key words
Mycoplasma pneumoniae pneumonia/Tumor necrosis factor-α/Interleukin-6/Galctin-3/Child引用本文复制引用
田芳,韩波,段梅..肺炎支原体肺炎患儿血清TNF-α、IL-6及半乳凝素3浓度测定的临床意义[J].中国当代儿科杂志,2014,(10):1001-1004,4.
