中国当代儿科杂志Issue(11)：1138-1142,5.DOI:10.7499/j.issn.1008-8830.2014.11.014
2010年江苏淮安基于出生人口新生儿呼吸衰竭流行病学调查
A population-based epidemiological survey of neonatal respiratory failure in Huai'an City of Jiangsu Province, in 2010
摘要
Abstract
Objective To investigate the prevalence, clinical characteristics, treatment, and prognosis of neonatal respiratory failure (NRF) in Huai’an, Jiangsu Province, China, in 2010. Methods The clinical data of all NRF cases in the hospitals of Huai’an in 2010 were prospectively collected and analyzed using descriptive epidemiological methods. Results Among 60 986 live births in Huai’an in 2010, there were 556 (0.91%) cases of NRF. The average birth weight of newborns with NRF was 2 433±789 g, with 53.8%determined as low birth weight and 64.1%as preterm. The major causes of NRF were respiratory distress syndrome, pneumonia, asphyxia, sepsis, and pulmonary hemorrhage. Among the newborns with NRF, 23.7%were accompanied by certain birth defects. Fourteen percent of newborns with NRF received pulmonary surfactant (PS) therapy, and the median time of the ifrst dose of PS was 5 hours (range:0-51 hours). Nasal continuous positive airway pressure treatment, conventional mechanical ventilation, and high-frequency ventilation were used in 67.9%, 33.3%, and 13.7%of patients, respectively. The cure and improvement rate of NRF patients was 73.9%(411/556), and the mortality rate was 22.5%(125/556). The average hospitalization expenses were 9 270 (range:196-38182) Yuan. Conclusions High morbidity, high mortality and high medical costs make NRF a serious challenge in Huai’an. It is essential to improve the quality of perinatal care and develop new techniques and new models in neonatal respiratory therapy in order to reduce the morbidity and mortality of NRF.关键词
呼吸衰竭/流行病学调查/新生儿Key words
Respiratory failure/Epidemiologic survey/Neonate引用本文复制引用
潘兆军,丁素芳,高子波,赵玉祥,韩良荣,岳虹霓..2010年江苏淮安基于出生人口新生儿呼吸衰竭流行病学调查[J].中国当代儿科杂志,2014,(11):1138-1142,5.基金项目
淮安市科技支撑项目（HAS2010013）。 （）
