中国当代儿科杂志Issue(12)：1250-1254,5.DOI:10.7499/j.issn.1008-8830.2014.12.013
儿童急性肝功能衰竭短期预后的影响因素
Short-term prognostic factors in children with acute liver failure
裴亮 1文广富 1郭张妍 1宋文良 1王丽杰 1刘春峰1
作者信息
- 1. 中国医科大学附属盛京医院PICU，辽宁 沈阳 110004
- 折叠
摘要
Abstract
ObjectiveTo investigate the factors that inlfuence the short-term (6 months) prognosis in children with acute liver failure.MethodsThe clinical information of 53 children with acute liver failure treated between June 2008 and September 2013 was retrospectively analyzed. The patients were divided into survival group (n=21) and death group (n=32) according to their outcomes. The liver function parameters and incidence of complications were compared between the two groups, and multivariate logistic regression analysis was used to identify major factors affecting the short-term prognosis in these patients.ResultsThere were significant differences between the death and survival groups in the indices of international normalized ratio (INR), blood ammonia and serum albumin (Alb), and complications such as hepatic encephalopathy, gastrointestinal hemorrhage, and multiple organ failure (P<0.05). Multivariate logistic regression analysis demonstrated that serum Alb, INR, and hepatic encephalopathy were the major factors affecting the short-term prognosis of acute liver failure (OR=0.616, 75.493 and 1210.727 respectively;P<0.05). ConclusionsINR, hepatic encephalopathy and serum Alb are the major factors that inlfuence the short-term prognosis in children with acute liver failure.关键词
急性肝功能衰竭/预后因素/儿童Key words
Acute liver failure/Prognostic factor/Child引用本文复制引用
裴亮,文广富,郭张妍,宋文良,王丽杰,刘春峰..儿童急性肝功能衰竭短期预后的影响因素[J].中国当代儿科杂志,2014,(12):1250-1254,5.
