中国当代儿科杂志Issue(5)：440-444,5.DOI:10.7499/j.issn.1008-8830.2015.05.005
不同程度支气管肺发育不良早产儿的临床及影像学特点
Clinical and imaging features of premature infants with different degrees of bronchopulmonary dysplasia
任艳丽 1孔祥永 2杜志方 1封志纯 3黄俊谨 1陈佳 1张珊1
作者信息
- 1. 南方医科大学北京军区总医院临床医学院附属八一儿童医院，北京 100007
- 2. 福建医科大学教学医院福建省妇幼保健院新生儿科，福建 福州 350001
- 3. 中国人民解放军白求恩国际和平医院儿科，河北 石家庄 050082
- 折叠
摘要
Abstract
ObjectiveTo study the clinical and imaging features of premature infants with different degrees of bronchopulmonary dysplasia (BPD).MethodsA prospective study was performed on the clinical data of 59 premature infants (gestational age <32 weeks) with BPD. Among the 59 premature infants, 37 cases had mild BPD and the other 22 cases had moderate to severe BPD. The clinical and imaging data were compared between these premature infants with different degrees of BPD.ResultsThe durations of mechanical ventilation, oxygen therapy, antibiotic therapy, parenteral nutrition, and hospitalization in the moderate to severe group were signiifcantly longer than those in the mild group (P<0.05). The incidence of nosocomial infection and number of times of red blood cell transfusion in the moderate to severe group were significantly higher than that in the mild group. The rates of X-ray changes, including grade I respiratory distress syndrome (1 day after birth) and hypolucency of lungs (4-10 days and≥28 days after birth) were signiifcantly higher in the mild group than in the moderate to severe group. The rates of X-ray changes in classical BPD stage III (4-10 days after birth) and IV (≥28 days after birth) were signiifcantly higher in the moderate to severe group than in the mild group.ConclusionsThe durations of mechanical ventilation, oxygen therapy, and antibiotic therapy and the incidence of nosocomial infection are correlated with the severity of BPD. The premature infants with severer BPD need a longer duration of parenteral nutrition and more times of red blood cell transfusion and have more typical imaging changes of BPD. Imaging examination has a predictive value for the severity of BPD.关键词
支气管肺发育不良/胸部X线检查/胸部CT扫描/新生儿Key words
Bronchopulmonary dysplasia/Chest X-ray/Chest CT scan/Neonate引用本文复制引用
任艳丽,孔祥永,杜志方,封志纯,黄俊谨,陈佳,张珊..不同程度支气管肺发育不良早产儿的临床及影像学特点[J].中国当代儿科杂志,2015,(5):440-444,5.
