TARC/CCL17基因多态性与川崎病及其临床特征的相关性分析OA北大核心CSCDCSTPCD
Association of single nucleotide polymorphisms in TARC/CCL17 gene with Kawasaki disease and its clinical characteristics
目的：探讨我国中部汉族人群中TARC/CCL17基因的SNP位点（rs223895、rs223899）多态性与川崎病（Kawasaki disease, KD）及其临床特点的关系。方法采用病例对照研究方法，选取218例典型KD患儿和248例体检正常儿童作为研究对象。利用PCR-RFLP的方法测定SNP位点多态性分布；评估TARC/CCL17基因多态性与KD临床特点的相关性。结果 KD患儿SNP位点（rs223895）的基因型（CC、CT、TT）频…查看全部>>
ObjectiveTo study the association of single nucleotide polymorphisms (SNPs, rs223895 and rs223899) in TARC/CCL17 gene with Kawasaki disease (KD) and its clinical characteristics in Han children from Central China.MethodsA case-control study was performed on 218 children with KD and 248 normal control children. The genotypes of SNPs (rs223895 and rs223899) in TARC/CCL17 gene were determined by polymerase chain reaction-restriction fragment length polymorphism…查看全部>>
刘凡;丁艳;尹薇
武汉市儿童医院，湖北 武汉 430016武汉市儿童医院，湖北 武汉 430016武汉市儿童医院，湖北 武汉 430016
川崎病TARC/CCL17基因易感性临床特征儿童
Kawasaki diseaseTARC/CCL17 geneSusceptibilityClinical characteristicsChild
《中国当代儿科杂志》 2015 (7)
668-671,4
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