中国肺癌杂志Issue(7)：569-574,6.DOI:10.3779/j.issn.1009-3419.2014.07.13
非小细胞肺癌中EMT的发生机制及预后价值的研究进展
Advances in the Molecular Mechanisms and Prognostic Signiifcance of EMT in Non-small Cell Lung Cancer
摘要
Abstract
Epithelial to mesenchymal transition (EMT) has an important role in the development of embryo, as well as that in the metastasis of non-small cell lung cancer (NSCLC). Recent researches have demonstrated that both morpho-logical and phenotypic conversions emerge in cells undergoing EMT. As most of relevant studies were on other cancers, it is es-sential to uncover whether it is the similar mechanisms accounting for EMT in NSCLC. With the progress of the studies, EMT-related basic researches are gradually applied to predicting the prognosis of NSCLC. hTe aim of this article was to discuss the mechanisms related to EMT emerging in NSCLC.关键词
肺肿瘤/上皮细胞-间叶细胞转化/机制/预后Key words
Lung neoplasms/Epithelial to mesenchymal transition/Mechanism/Prognosis引用本文复制引用
曹勤琛,赵路军,王平..非小细胞肺癌中EMT的发生机制及预后价值的研究进展[J].中国肺癌杂志,2014,(7):569-574,6.基金项目
This study was supported by the grant from Tianjin Key Problem Tackling Project for Cancer Therapy (to Ping WANG)(No.12ZCDZSY15900) （to Ping WANG）
