摘要
Abstract
Objective To investigate the changing trends in 4 continuous point prevalence surveys of healthcare-as-sociated infection(HAI)in a hospital. Methods The occurrence of HAI among all hospitalized patients were inves-tigated on a given day from 0:00 to 24:00 in May,2006,2008,2010,and 2012 respectively.Results A total of 4 497 patients should be investigated,4 387 (97.55% )patients were actually investigated;184 patients developed 209 times of HAI,point prevalence rate of HAI was 4.19% ,case prevalence rate was 4.76% . Trendχ2 test showed that HAI prevalence rate decreased gradually from 5.56% in 2006 to 2.76% in 2012(χ2= 14.07,P<0.001).The main infection site was lower respiratory tract (55.03% ),followed by urinary tract(14.83% )and upper respiratory tract(9.57% ).The overall usage rate of antimicrobial agents was 38.50% . Trendχ2 test showed that usage rate of antimicrobial agents decreased gradually from 2006 to 2012(χ2= 5.13,P= 0.023);pathogenic detection rate in pa-tients receiving therapeutic and therapeutic plus prophylactic antimicrobial use increased gradually(χ2= 40.81 ,P<0.001);single use of antimicrobial agents increased gradually(χ2= 23.86,P<0.001). The rate of arteriovenous in-tubation ,urinary catheterization ,respirator use,and venous intubation in patients with HAI was significantly higher than those without HAI (27.17% vs 9.80% ,35.33% vs 11.54% ,13.59% vs 4.33% ,84.78% vs 63.24%respectively ,all P<0.001). Conclusion Management of rational use of antimicrobial agents has been achieved re-markably,control of HAI improved continuously;but control of invasive procedure-associated infection need to be intensified,management of rational use of antimicrobial agents should be paid much attention.关键词
现患率/医院感染/抗菌药物/感染控制/合理用药Key words
Kex words] point prevalence/healthcare-associated infection/antimicrobial agent/infection control/rational drug use分类
医药卫生
