中国感染控制杂志Issue(8)：454-457,4.DOI:10.3969/j.issn.1671-9638.2014.08.002
一起 MRSA 感染流行病学调查
Epidemiological investigation on an epidemic of methicillin-resistant Staphylococcus aureus infection
沈雪莲 1范超云 1许慧 1熊祝嘉 1钟秀玲1
作者信息
摘要
Abstract
Objective To investigate transmission routes of healthcare-associated infection(HAI)caused by methi-cillin-resistant Staphylococcus aureus (MRSA),and make effective measures for preventing and controlling the oc-currence and epidemic of HAI caused by multidrug-resistance bacteria.Methods From February 24 to March 29, 2012,12 MRSA-infected patients were performed epidemiological study,these patients underwent bronchoscopy be-cause of tracheal stenosis,strains were identified by amplifying the sequences of 16S rRNA ,femA and mecA with real-time quantitative polymerase chain reaction (PCR),homology analysis of strains were performed by Spa geno-typing.Results All 12 MRSA-infected patients were susceptible to multidrug-resistance bacterial infection,5 cases of MRSA infection occurred during this hospitalization.Detection of specimens from health care workers and envi-ronment were all negative;Spa gene of all 12 MRSA isolates was type t 030 ,which was the main epidemic strain in Asia;Spa gene of Staphylococcus aureus isolated from nurses’noses was type t1425 .Conclusion The assumption of MRSA spread among health care workers aren’t supported by the epidemiological investigation results,genotypes of 12 MRSA isolates are identical,but the result of gene typing can’t be as the evidence of homology of infection ;patients at high risk for MRSA infection should be screened as early as possible,early contact isolation should be performed,so as to prevent and control the occurrence of HAI.关键词
金黄色葡萄球菌/耐甲氧西林金黄色葡萄球菌/医院感染/流行病学/感染控制Key words
Staphylococcus aureus/methicillin-resistant Staphylococcus aureus/healthcare-associated infection/epidemiology/infection control分类
医药卫生引用本文复制引用
沈雪莲,范超云,许慧,熊祝嘉,钟秀玲..一起 MRSA 感染流行病学调查[J].中国感染控制杂志,2014,(8):454-457,4.
