中国感染控制杂志Issue(9)：530-533,4.DOI:10.3969/j.issn.1671-9638.2014.09.004
难愈性创面感染耐甲氧西林金黄色葡萄球菌危险因素
Risk factors for methicillin-resistant Staphylococcus aureus infection of refractory wound
摘要
Abstract
Objective To explore the risk factors for methicillin-resistant Staphylococcus aureus (MRSA)infection of refractory wound,and provide reference for clinical prevention and control.Methods Clinical data of patients who were isolated Staphylococcus aureus (SA)from wound at the burn ward in a hospital from January 2006 to December 2013 were analyzed,patients were divided into four groups according to whether the isolated SA were MRSA and whether SA were from refractory wound or from non-refractory wound.Risk factors for MRSA infection of refractory wound were analyzed. Results A total of 112 isolates of SA were isolated from wound,statistical differences existed in the length of hospital stay,recent invasive operation,and recent antimicrobial use between patients in refractory wound MRSA group and refrac-tory wound methicillin-sensitive SA (MSSA)group (all P <0.05);non-conditional logistic regression analysis revealed that length of hospital stay>30 days (OR 95% CI :1.14-30.69)and recent invasive operation (OR 95% CI :1.41 -17.84) were independent risk factors for refractory wound MRSA infection.There were statistically differences in previous MRSA infection,burn depth,recent operation and recent antimicrobial use between refractory wound MRSA group and non-refrac-tory wound MRSA group(all P <0.05);non-conditional logistic regression analysis revealed that recent antimicrobial use (OR 95% CI :2.080-26.800)was independent risk factor for the persistence of MRSA infection of refractory wound. Conclusion Shortening the length of hospital stay,reducing invasive operation,and using antimicrobial agents ra-tionally are helpful for the prevention and control of MRSA infection of refractory wound.关键词
烧伤/创面,难愈性/金黄色葡萄球菌/耐甲氧西林金黄色葡萄球菌/危险因素/医院感染/感染控制Key words
burn/wound,refractory/Staphylococcus aureus/methicillin-resistant Staphylococcus aureu/risk factor/healthcare-associated infection/infection control分类
医药卫生引用本文复制引用
倪俊,许献荣,陈瑞彩,张杏梅..难愈性创面感染耐甲氧西林金黄色葡萄球菌危险因素[J].中国感染控制杂志,2014,(9):530-533,4.基金项目
上海市卫生局科研基金 （）
