中国感染控制杂志Issue(2)：85-88,4.DOI:10.3969/j.issn.1671-9638.2015.02.004
某院2009-2013年鲍曼不动杆菌临床分布及耐药性变迁
Clinical distribution and change in drug resistance of Acinetobacter bau-mannii in a hospital in 2009-2013
摘要
Abstract
Objective To analyze clinical distribution and change in drug resistance of Acinetobacter baumannii (A.baumannii)in 2009-2013,guide clinical rational antimicrobial use,and reduce healthcare-associated infection rate.Methods 919 A.baumannii isolates were isolated from inpatients and outpatients in a hospital between Janu-ary 2009 and December 2013,specimen and department sources,as well as change in drug resistance of A.bauman-nii were analyzed.Results A total of 10 273 pathogens were isolated from 2009 to 2013,the constituent ratio of A.baumannii in each year was 7.98%(n=93),11.31%(n=155),10.22%(n=185),7.73%(n=217),and 8.62%(n=269)respectively;the constituent ratio of imipenem-resistant A.baumannii was 24.73%,38.06%,71.89%, 64.52%,and 86.99% respectively;the main specimen source was sputum (83.68%);the major department sources were intensive care unit(ICU,39.28%),department of neurology (20.78%),and department of respiratory medi-cine(8.60%).The resistant rate of A.baumannii to most antimicrobial agents increased,the resistant rates to imi-penem and piperacillin/tazobactam increased from 24.73% and 4.44% in 2009 to 86.99% and 86.25% in 2013 re-spectively;resistant rate to sulphamethoxazole/trimethoprim decreased from 91.30% in 2009 to 27.14% in 2013;in 2013,except resistant rates to amikacin and sulphamethoxazole/trimethoprim were low (20.82% and 27.14%respectively),resistant rates to the other 11 kinds of antimicrobial agents were all >83.64%.Conclusion The iso-lation rate of A.baumannii is high in this hospital,the main specimen source is sputum,the main department source is ICU;antimicrobial resistant rate of A.baumannii is high,prevention and control of infection and trans-mission of A.baumannii should be strengthened.关键词
鲍曼不动杆菌/抗药性,微生物/合理用药/抗菌药物/医院感染Key words
Acinetobacter baumannii/drug resistance,microbial/rational antimicrobial use/antimicrobial agent/healthcare-associated infection分类
医药卫生引用本文复制引用
赵建平,周秀岚..某院2009-2013年鲍曼不动杆菌临床分布及耐药性变迁[J].中国感染控制杂志,2015,(2):85-88,4.基金项目
2013年内蒙古自治区自然基金立项资助项目 （）
