局解手术学杂志Issue(2)：138-139,140,3.DOI:10.11659/jjssx.09E014014
正性脾自体移植对DEN诱发大鼠肝癌的治疗作用
Therapeutic effect of splenic autologous transplantation on rat liver cancer induced by DEN
韩殿冰 1梁玲 2张朝阳 3赵刚 3冯大猛3
作者信息
- 1. 汝州市第四人民医院肝胆外科，河南 汝州467500
- 2. 临沂市妇幼保健院药剂科，山东 临沂276000
- 3. 汝州市第一人民医院普通外科，河南 汝州467500
- 折叠
摘要
Abstract
Objective To investigate the therapeutic effect of autologous transplantation of spleen on rat liver cancer induced by DEN. Methods Forty rats were randomly divided into A and B group on average. Total spleens of 40 rats were resected, which preserved in liquid nitrogen. All splenectomy rats were feeded with DEN to induce hepatocellular carcinoma. After 12 weeks ,all rats which had were successfully induced liver cancer were transplanted by autologous spleen in group A. Group B were sham operation as control. Results Survival period was significantly higher in group A than that in group B. But transplanted splenic tissue had not recovered to normal morphological structure until these rats died. Conclusion Autologous transplantation of spleen has therapeutic effect for liver cancer induced by DEN.关键词
脾/移植/肝癌/治疗Key words
spleen/transplantion/liver cancer/treatment分类
医药卫生引用本文复制引用
韩殿冰,梁玲,张朝阳,赵刚,冯大猛..正性脾自体移植对DEN诱发大鼠肝癌的治疗作用[J].局解手术学杂志,2015,(2):138-139,140,3.
