局解手术学杂志Issue(3)：327-329,3.DOI:10.11659/jjssx.06E014328
呼末二氧化碳指导新西兰大白兔机械通气的研究
Leading effect of PETCO2 on mechanical ventilation in New Zealand white rabbits
杨俊哲 1张燕辉 1吴明春 1陶军 1宋晓阳 1罗中兵1
作者信息
- 1. 广州军区武汉总医院麻醉科，湖北 武汉430070
- 折叠
摘要
Abstract
Objective To observe the leading effect of end-tidal pressure of carbon dioxide in artery ( PET CO2 ) on mechanical ventila-tion in New Zealand white rabbits, and to establish parameters for medical animal experiments in terms of hemodynamics, blood gas, blood glucose, electrolyte. Methods 31 anesthetized New Zealand rabbits were practiced tracheostomy tube and mechanical ventilation. Respira-tion rate was 40 breaths/min and tidal volume was adjusted so that PET CO2 was 29 mmHg. Invasive blood pressure, electrocardiogram and PET CO2 were monitored. Blood gas analysis, electrolyte, hemoglobin and blood glucose were tested. Results When PET CO2 was maintained at 29 mmHg, the results were as follows:PH (7.42 ±0.07), 95% confidenceinterval (7.40~7.45);PaCO2(38.5 ±5.8) mmHg, 95%confidenceinterval (36. 4~40. 6) mmHg;BE (1. 45 ± 2. 80) mmol/L,95% confidenceinterval (0. 43~2. 48) mmHg. Conclusion Moni-toring of PET CO2 is good to guide mechanical ventilation in New Zealand white rabbits.关键词
兔/呼末二氧化碳分压/机械通气/电解质/血气分析/血流动力学Key words
rabbit/end-tidal pressure of carbon dioxide in artery/mechanical ventilation/electrolyte/blood gas analysis/hemodynamics分类
医药卫生引用本文复制引用
杨俊哲,张燕辉,吴明春,陶军,宋晓阳,罗中兵..呼末二氧化碳指导新西兰大白兔机械通气的研究[J].局解手术学杂志,2015,(3):327-329,3.
