中国康复Issue(1)：7-9,3.DOI:10.3870/zgkf.2015.01.002
电针丰隆穴对高脂血症大鼠血脂及肝脏组织炎症细胞因子的调控作用
Modutory effect of electroacupuncture at "Fenglong"(ST40)on blood lipid and inflammatory factors in livers of rat hy-perlipidemia model
摘要
Abstract
Objective:To study the modutory effect of electroacupuncture at the "Fenglong"on inflammatory fac‐tors in the livers of rat hyperlipidemia model .Methods :Thirty health male SD rats were selected and randomly di‐vided into 3 groups :normal control group (A) ,model control group (B) ,and electroacupuncture group (C) .After four weeks ,blood lipids of rats were determined .The protein levels of TNF‐α,IL‐1βand IFN‐γin the livers of rat hyperlipidemia model were detected by ELISA .Results:As compared with group A ,the contents of TC ,TG and LDL‐C were significantly increased (P<0 .01 ,or P<0 .05) and the content of HDL‐C was significantly decreased (P<0 .05) in group B ,and the contents of TC and LDL‐C were significantly increased in group C (P<0 .01) .As compared with group B ,the contents of TC ,TG and LDL‐C were significantly reduced (P<0 .01) ,and those of HDL‐C significantly increased in group C (P<0 .05) .As compared with group A ,TNF‐α,IL‐1βand IFN‐γlevels were increased significantly in group B (P<0 .05 ,and P<0 .01) .As compared with group B ,TNF‐α,IL‐1βand IFN‐γlevels in group C were decreased significantly (P<0 .05 ,and P<0 .01) .Conclusion:Electroacupuncture at "Fenglong"can notably decrease the levels of TC and LDL‐C ,and the protein levels of TNF‐α,IL‐1βand IFN‐γin the liver tissues ,suggesting its certain therapeutical effectiveness on hyperlipemia .关键词
高脂血症/电针/丰隆穴/肿瘤坏死因子-α/白细胞介素-1β/干扰素-γKey words
hyperlipemia/electroacupuncture/Point ST40 (Fenglong)/TNF-α/IL-1β/IFN-γ分类
医药卫生引用本文复制引用
乐薇,张红星,王琼,黄国付,周利,覃鹏飞..电针丰隆穴对高脂血症大鼠血脂及肝脏组织炎症细胞因子的调控作用[J].中国康复,2015,(1):7-9,3.基金项目
国家自然科学基金项目 （）
