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A 型肉毒毒素治疗对痉挛型脑瘫患儿足底压力改变的影响

李金玲 徐开寿 严晓华 李翠玲 郑韵 郑玉蔼

中国康复Issue(3):195-197,3.
中国康复Issue(3):195-197,3.DOI:10.3870/zgkf.2015.03.010

A 型肉毒毒素治疗对痉挛型脑瘫患儿足底压力改变的影响

Effects of botulinum toxin injection on foot pressure in children with spastic cerebral palsy

李金玲 1徐开寿 1严晓华 1李翠玲 1郑韵 1郑玉蔼1

作者信息

  • 1. 广州市妇女儿童医疗中心康复科,广州 510120
  • 折叠

摘要

Abstract

Objective:To compare the effects of botulinum toxin A (BTX‐A ) injection plus physiotherapy ,or physiotherapy alone on the food pressure in children with spastic cerebral palsy (SCP) .Methods:213 children with SCP were randomly divided into two groups :BTX‐A group (BTX‐A injections combined with physical therapy ,108 cases) and control group (physical therapy ,105 cases) .Two groups received 2 weeks of hospital‐based physiothera‐py ,and 10 weeks of home‐based physiotherapy .Outcome assessments included foot pressure measured by GHW type plantar pressure tester ,modified Ashworth scale (MAS) ,D and E dimensions of the Gross Motor Function Measure (GMFM ) ,and physician rating scale was determined before and 2 ,12 weeks after treatment .Results:Children in BTX‐A group showed an improvement of foot pressure ,spasticity ,standing and walking ,gait 2 and 12 weeks after treatment as compared with those before treatment (P<0 .05) .These scores in control group were im‐proved at 12th week only .Furthermore ,there was significant difference in foot pressure ,spasticity ,standing and walking ,gait between two groups at 12th week (P<0 .05) .Conclusion:BTX‐A injection combined with physical therapy was advantageous in improving foot pressure ,spasticity ,walking ,and gait in children with SCP .

关键词

A型肉毒毒素/脑性瘫痪/痉挛/足底压力/物理治疗

Key words

botulinum toxin A/cerebral palsy/spasticity/foot pressure/physiotherapy

分类

医药卫生

引用本文复制引用

李金玲,徐开寿,严晓华,李翠玲,郑韵,郑玉蔼..A 型肉毒毒素治疗对痉挛型脑瘫患儿足底压力改变的影响[J].中国康复,2015,(3):195-197,3.

中国康复

OACSTPCD

1001-2001

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