中国康复理论与实践Issue(6)：543-547,5.DOI:10.3969/j.issn.1006-9771.2014.06.010
正常人脑静息态功能磁共振的脑功能连接1
Effective Connectivity of Resting-state Functional Magnetic Resonance Imaging in Normal Adults
摘要
Abstract
Objective To detect the effective connectivity of resting-state functional magnetic resonance imaging (fMRI) in normal adults. Methods 36 normal adults were performed resting-state fMRI scanning, and 5 brain netwokes were included as regions of interests. Independent component (ICA) was used to evaluate the effective connectivity, and multivariate Granger causality analysis (mGCA) was used to analyze the casuality between the networks. All preprocessing steps were carried out using Statistical Parametric Mapping 5.0 soft-ware. Results 5 classic resting brain networks including default mode network (DMN), memory network (MeN), motor network (MoN), au-ditory network (AN) and executive control network (ECN) were aquired. The mGCA presented significant casuality between DMN and oth-er 4 networks, MeN and ECN, AN and MoN, ECN and AN. Conclusion There are specific brain effective connectivity of resting-state fMRI in normal adults, and there is significant causal link between these networks.关键词
静息态功能磁共振成像/脑功能连接/独立成分分析Key words
resting-state functional magnetic resonance imaging/brain network connection/independent component analysis分类
医药卫生引用本文复制引用
石庆丽,燕浩,陈红燕,王凯,姚婧璠,韩在柱,张玉梅,张贵云,高玉苹..正常人脑静息态功能磁共振的脑功能连接1[J].中国康复理论与实践,2014,(6):543-547,5.基金项目
1.国家社科基金重大项目(No.11&ZD186)；2.北京市卫生系统高层次卫生技术人才培养计划项目(No.2011-3-024)；3.北京市科委项目(No. D101107049310005 （No.11&ZD186）
No. Z121100005512016)；4.国家科技支撑计划项目(No.2011BAI08B02)。 （No.2011BAI08B02）
