中国康复理论与实践Issue(11)：1063-1067,5.DOI:10.3969/j.issn.1006-9771.2014.11.017
急性缺血性脑卒中患者血清脂蛋白（a）水平及临床意义
Significance of Serum Lipoprotein(a) in Patients with Acute Ischemic Stroke
贾淑芬 1李洪利2
作者信息
- 1. 中国康复研究中心北京博爱医院检验科，北京市100068
- 2. 清华大学医院，北京市100083
- 折叠
摘要
Abstract
Objective To investigate the serum lipoprotein (Lp) (a) level in patients with acute ischemic stroke and the prediction for short-term functional outcome. Methods The levels of serum Lp(a) were measured in 210 patients with acute ischemic stroke (within 24 h after onset) and 100 healthy people matched the gender and age. The patients were assessed with National Institutes of Health Stroke Scale (NIHSS) as admission, and modified Rankin Scale (mRS) as discharge. Results The median of Lp(a) was 325 mg/L (IQR:180~545) in pa-tients, significantly more than 148 mg/L (IQR:69~265) in the normal controls (P<0.001). Level of serum Lp(a) was an independent variable for functional outcome (OR=1.004, 95%CI:1.001~1.007, P<0.001) and death (OR=1.006, 95%CI:1.001~1.008, P<0.001) in patients. In the receiver operating characteristic curve, the area under curve was more in the combined model [Lp(a) and NIHSS] than the NIHSS alone. Conclusion Serum Lp(a) increased in the in patients with acute ischemic stroke, and may predict the short-term outcome independently.关键词
脑卒中/急性/缺血/脂蛋白(a)/短期/预后Key words
stroke/acute/ischemia/lipoprotein(a)/short-term/outcome分类
医药卫生引用本文复制引用
贾淑芬,李洪利..急性缺血性脑卒中患者血清脂蛋白（a）水平及临床意义[J].中国康复理论与实践,2014,(11):1063-1067,5.
