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颈椎病慢性疼痛患者的默认网络研究

张华 王昊 李多多 贾宝林 谭中建 陈红

中国康复理论与实践Issue(1):69-73,5.
中国康复理论与实践Issue(1):69-73,5.DOI:10.3969/j.issn.1006-9771.2015.01.018

颈椎病慢性疼痛患者的默认网络研究

Default Mode Network Altered in Chronic Pain Caused by Cervical Spondylosis

张华 1王昊 2李多多 2贾宝林 2谭中建 3陈红2

作者信息

  • 1. 北京中医药大学东直门医院 神经内科,北京市100700
  • 2. 北京中医药大学东直门医院 推拿科,北京市100700
  • 3. 北京中医药大学东直门医院 放射科,北京市100700
  • 折叠

摘要

Abstract

Objective To explore the changes of resting state default mode network (DMN) in patients with chronic pain caused by cer-vical spondylosis (CPCS). Methods 8 healthy controls and 10 patients accepted functional MRI scanning. Surface based DMN was extract-ed with independent component analysis (ICA). The functional connectivity of the components of DMN were discriminated with support vector machine (SVM) algorithm from the patients to the controls. Results The DMN connectivity was different in the patients from the con-trols in some of the component areas. Conclusion DMN of CPCS patients is disorder in multiple brain areas, which may be involved with dysfunction of perception processing, emotion and memory.

关键词

颈椎病/慢性疼痛/默认网络/支持向量机/独立成分分析

Key words

cervical spondylosis/chronic pain/default mode network/support vector machine/independent component analysis

分类

医药卫生

引用本文复制引用

张华,王昊,李多多,贾宝林,谭中建,陈红..颈椎病慢性疼痛患者的默认网络研究[J].中国康复理论与实践,2015,(1):69-73,5.

基金项目

北京中医药大学中青年教师资助项目(No.2013-JYBZZ-JS-047)。 (No.2013-JYBZZ-JS-047)

中国康复理论与实践

OA北大核心CSCDCSTPCD

1006-9771

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