中国康复理论与实践Issue(1):69-73,5.DOI:10.3969/j.issn.1006-9771.2015.01.018
颈椎病慢性疼痛患者的默认网络研究
Default Mode Network Altered in Chronic Pain Caused by Cervical Spondylosis
摘要
Abstract
Objective To explore the changes of resting state default mode network (DMN) in patients with chronic pain caused by cer-vical spondylosis (CPCS). Methods 8 healthy controls and 10 patients accepted functional MRI scanning. Surface based DMN was extract-ed with independent component analysis (ICA). The functional connectivity of the components of DMN were discriminated with support vector machine (SVM) algorithm from the patients to the controls. Results The DMN connectivity was different in the patients from the con-trols in some of the component areas. Conclusion DMN of CPCS patients is disorder in multiple brain areas, which may be involved with dysfunction of perception processing, emotion and memory.关键词
颈椎病/慢性疼痛/默认网络/支持向量机/独立成分分析Key words
cervical spondylosis/chronic pain/default mode network/support vector machine/independent component analysis分类
医药卫生引用本文复制引用
张华,王昊,李多多,贾宝林,谭中建,陈红..颈椎病慢性疼痛患者的默认网络研究[J].中国康复理论与实践,2015,(1):69-73,5.基金项目
北京中医药大学中青年教师资助项目(No.2013-JYBZZ-JS-047)。 (No.2013-JYBZZ-JS-047)