中国康复理论与实践Issue(3):272-275,4.DOI:10.3969/j.issn.1006-9771.2015.03.007
热射病大鼠的学习记忆功能研究
Learning and Memory Function of Rats after Heat Stroke
摘要
Abstract
Objective To observe the learning and memory function of rats after heat stroke. Methods 60 Sprague-Dawley rats were di-vided randomly into heat stroke group (n=44), sham group (n=8) and control group (n=8). They were tested with the Morris Water Maze 7 days after modeling. The escaping latency was recorded in the first 5 days, and it was recorded with frequency crossing the platform area and the duration in the target quadrant after ridding the platform on the 6th day. Results 16 rats died in the heat stroke group after modeling. The escaping latency increased (P<0.05), and the cumulative duration in the target quadrant and the frequency of crossing the previous plat-form decreased (P<0.05) in the heat stroke group compared with the other groups. Conclusion The learning and memory ability is impaired after heat stroke in rats.关键词
热射病/Morris水迷宫/学习记忆/认知功能/大鼠Key words
heat stroke/Morris Water Maze/learning and memory/cognitive function/rats分类
医药卫生引用本文复制引用
张进进,王恒,房效莉,周立冬,吴士文..热射病大鼠的学习记忆功能研究[J].中国康复理论与实践,2015,(3):272-275,4.基金项目
国家发改委卫星专项基金项目(No.发改办高技[2013]2140)。 (No.发改办高技[2013]2140)