中国康复理论与实践Issue(3)：303-306,4.DOI:10.3969/j.issn.1006-9771.2015.03.014
脑电仿生电刺激对持续植物状态患者脑血流速度和脑代谢的影响
Effect of Electroencephalograph Bionic Electrical Stimulation on Persistent Vegetative State：Cerebral Blood Flow and Metabolism
摘要
Abstract
Objective To study the effect of electroencephalograph (EEG) bionic electrical stimulation at Wangu (GB12), Tianzhu (BL10), Neiguan (PC6) on cerebral blood flow and metabolism in patients with persistent vegetative state (PVS). Methods 60 patients with PVS were divided into observation group (n=30) and control group (n=30) according to the random number table. The control group re-ceived routine treatment, including basic management, hyperbaric oxygen therapy, awaking medicine, sensory stimulation, and so on;while the observation group received EEG bionic electrical stimulation at bilateral Tianzhu, Wangu (cheif electrodes) and Neiguan (auxiliary elec-trodes) in addition. They were treated for 30 days. They were assessed with the PVS score, and observed with transcranial Doppler ultra-sound (TCD) and magnetic resonance spectroscopy (MRS) one day before and one day after treatment. Results The incidence of improve-ment was 86.67%in the observation group, more than 60.00%in the control group (P<0.05). The difference of blood flow velocity before and after treatment (ΔVm) of anterior-middle cerebral artery was more in the observation group than in the control group respectively (P<0.001), as well as those of posterior cerebral-vertebral-basilar artery (P<0.01). The N-acetyl aspartic acid/creatine (NAA/Cr) increased more in the observation group than in the control group respectively (P<0.01), and the choline/creatine (Cho/Cr) decreased more (P<0.01), after treatment. Conclusion EEG bionic electrical stimulation can improve the cerebral circulation and metabolism in patients with PVS, which may associate with the wake promoting.关键词
持续植物状态/脑电仿生电刺激/脑血流速度/脑代谢Key words
persistent vegetative state/electroencephalograph bionic electrical stimulation/cerebral blood flow velocity/cerebral me-tabolism分类
医药卫生引用本文复制引用
倪莹莹,邓丽霞,邱承尧,汪文胜,马梦良,刘云义..脑电仿生电刺激对持续植物状态患者脑血流速度和脑代谢的影响[J].中国康复理论与实践,2015,(3):303-306,4.基金项目
广东省中医药局科研课题(No.20122001)。 （No.20122001）
