中国临床药理学杂志Issue(5):436-437,472,3.
益气活血颗粒对心气虚证T淋巴细胞亚群影响的实验研究
Experimental study on influence of Yiqibuxue granuel on T lymphocyte subsets in rats with syndrome of heart-Qi insufficiency
摘要
Abstract
Objective To observe the influence of some Chinese herbal granules with the effects of replenishing Qi and activating blood on T lym-phocyte subsets in rats with syndrome of heart -Qi insufficiency.Meth-ods The models were established on rats , which were orally given Yiqibuxue granule with high , low doses ( 2.0 , 0.5 g/100 g ) and Tian-wangbuxin pills (1 g/100 g, control group ) and normal saline respective-ly,once a day for 7 days.The T lymphocyte subsets in peripheral blood and cardiac muscle in rats were observed.Results The model group was lower than the normal saline group on natural kill and wound cell ( CD3+) ,adjuvant T cell ( CD4+) ,higher than normal saline group on cell toxicity T cell( CD8+).There was a significant difference between model group and other groups ( P<0.01 ).There were significant differences ( P<0.01 ) between the high -dose group and the control group.Conclu-sion The Yiqibuxue granules with the effects of replenishing Qi and ac-tivating blood are effective in raising CD 3+、CD4+and reducing CD 8+.关键词
心气虚证/益气活血颗粒/天王补心丸Key words
syndrome of heart -Qi insufficiency/Yiqibuxue granuel/Tianwangbuxin pill分类
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..益气活血颗粒对心气虚证T淋巴细胞亚群影响的实验研究[J].中国临床药理学杂志,2014,(5):436-437,472,3.基金项目
甘肃省科技厅科技支撑计划基金资助项目 ()