中国临床药理学杂志Issue(9)：759-761,3.DOI:10.13699/j.cnki.1001-6821.2014.09.002
参附注射液在颈动脉支架置入术中及术后对血压和心率的影响
Effect of Shenfu injection on blood pressure and heart rate during and after carotid artery stenting
摘要
Abstract
Objective To investigate the effects of Shenfu injection on blood pressure and heart rate of patients receiving carotid artery stenting.Methods One hundred and twenty patients were randomly divided into the treatment group and the control group , sixty cases in each group.The control group received conventional medication under custodial care , and the treatment group was given Shenfu ( 1 mL · kg -1 ) 10 minutes before surgery.Mean arterial pressure(MAP), heart rate (HR), oxygen satu-ration (SpO2), as well as the frequency of intra -operative hypotension, and the applications of ephedrine and atropine were recorded respectively at the beginning of surgery , the 30 th minute during surgery , the end of surgery and 24 hours after the surgery.Results The operations were all successful , and no adverse reactions occurred.MAP in treatment group at the 30th minute during surgery was higher than in the control group , while it was lower than of the control group at the end of surgery ( P<0.01).HR in the treatment group (68.25 ±7.35) times· min-1 was lower than that of the control group (73.28 ±10.43)times· min-1 at the end of surgery (P<0.05 ).Conclusion Shenfu injection helps stabilize blood pressure and heart rate of patients receiving carotid artery stenting through the two-way adjustment , and it could reduce the occurrence of cerebrovascu-lar accident during the per -operative period.关键词
颈动脉支架置入术/参附注射液/血压/心率Key words
carotid artery stenting/Shenfu injection/blood pressure/heart rate分类
医药卫生引用本文复制引用
范瑞明,陈仲琼,徐平,龚其海,姚声涛,李刚,王长明,曾尤超,焦松,夏湘平,韩冲,陈伟..参附注射液在颈动脉支架置入术中及术后对血压和心率的影响[J].中国临床药理学杂志,2014,(9):759-761,3.基金项目
教育部长江学者和创新团队发展计划基金资助项目 （）
