中国临床药理学杂志Issue(3)：196-198,3.DOI:10.13699/j.cnki.1001-6821.2015.03.012
罗哌卡因联合复方倍他米松用于脊柱手术术后镇痛的临床研究
Clinical study of ropivacaine combined with betamethasone in the postoperative analgesia of spine surgery
摘要
Abstract
Objective To investigate the analgesic effect of infiltration with ropivacaine combined with betamethasone in patients undergoing spinal surgery.Methods Eighty-three patients receiving spinal surgery were randomly divided into two groups.Patients in treatment group (n=43) were infiltrated with 0.75% ropivacaine 10 mL combined with betamethasone 1 mL and 1∶1 0.9%NaCl into the paravertebral muscles and subcutaneous tissues after sutured incision.Patients in control group (n=40) were given 0.9%NaCl 20 mL at same sites.The data of post-operative pain scores, wound healing and opioid drug usage were recorded.Results The data of VAS pain score and opioids dosage in the treatment group was much lower than those in control group ( P <0.05 ).There were 36 ( 83.7%) and 33 ( 82.5%) cases of class A healing in treatment group and control group , 6 ( 14.0%) and 5 (12.5%)cases of class B healing, and 1(2.3%) and 2(5.0%)cases of class C healing, but the incision healing grade between the two groups was not statistically different ( P >0.05 ).Conclusion Ropivacaine combined with betamethasone can significantly decrease the pain in patients undergoing spin surgery, without increasing the risk of cut infection.关键词
脊柱手术/罗哌卡因/复方倍他米松/镇痛Key words
spinal surgery/ropivacaine/diprospan/analgesic分类
医药卫生引用本文复制引用
李坚,曾云记,谢金兔,赵志刚..罗哌卡因联合复方倍他米松用于脊柱手术术后镇痛的临床研究[J].中国临床药理学杂志,2015,(3):196-198,3.基金项目
卫生部公益项目科研专项基金资助项目 （）
