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微小 RNA-9在癌症及神经退行性疾病中的研究现状

李晓琳 胡雪玲 孙丽华

中国临床药理学杂志Issue(4):315-316,320,3.
中国临床药理学杂志Issue(4):315-316,320,3.DOI:10.13699/j.cnki.1001-6821.2015.04.024

微小 RNA-9在癌症及神经退行性疾病中的研究现状

Research status of microRNA-9 in cancers and neurodegenerative disease

李晓琳 1胡雪玲 1孙丽华1

作者信息

  • 1. 哈尔滨医科大学 药学院 药理教研室,哈尔滨 150086
  • 折叠

摘要

Abstract

MicroRNA-9( miR-9) family is a kind of non-coding small single-stranded RNA, by participating in the genes of post-translational modifications to regulate gene expression.In recent years, the incidence of cancer rises year by year.To study its mechanism and treatment has great significance.According to recent studies, the quantity of miR-9 expression in many types of cancers is abnormal, suggesting miR-9 may be associated with the formation or development of tumors.This article mainly discuss the research progress of miR-9 in many cancers and nerve system diseases, emphasis on the effect of miR-9 in breast cancer, gastric cancer, colon cancer, esophagus cancer, neuroblastoma and neurodegenerative disease.

关键词

微小RNA-9/神经退行性疾病/癌症

Key words

microRNA-9/neurodegenerative disease/cancer

分类

医药卫生

引用本文复制引用

李晓琳,胡雪玲,孙丽华..微小 RNA-9在癌症及神经退行性疾病中的研究现状[J].中国临床药理学杂志,2015,(4):315-316,320,3.

基金项目

国家自然科学基金资助项目(81000499,81371211);哈尔滨医科大学药学院大学生创新基金资助项目 ()

中国临床药理学杂志

OA北大核心CSCDCSTPCD

1001-6821

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