中国临床药理学杂志Issue(5)：333-335,3.DOI:10.13699/j.cnki.1001-6821.2015.05.004
罗哌卡因局部麻醉对甲状腺术后镇痛的临床观察
Clinical study of local ropivacaine for post-operative pain after thyroid surgery
摘要
Abstract
Objective To investigate the effect of local ropivacaine on post-operative pain after thyroid surgery.Methods A total of 120 pa-tients undergoing thyroid surgery at the second affiliated hospital of xin-jiang medical university from February 2013 to February 2014 were ran-domly divided into 3 groups.Patients in group A were given 0.5%ropi-vacaine 10 mL infiltrated incision before operation and 10 mL sprayed be-fore suture.Patients in group B received 0.5%lidocaine in the same way with group A, and those in group C did not receive local anesthesia.The data of visual analog scores ( VAS) scores were recorded at 1, 4, 8, 12, 24 and 48 h after operation.Patients received tramadol 100 mg when VAS score was more than four, and the adverse reactions and condition of the wound healing were recorded after operation.Results The VAS scores at 4, 8, 12, 24 h after operation was significantly lower in group A compared with group B and C(P <0.05), and the VAS score at 1 h after operation were significantly higher in group C and B compared with group A(P<0.05).The amount of tramadol requirements was signifi-cantly higher in group B and C compared with group A ( P <0.05 ).Higher rates of nausea and vomiting were observed in group B and C ( P <0.05).There was no significant difference in the condition of wound healing among three groups( P>0.05 ).Conclusion Local use of 0.5%ropivacaine can significantly reduce post-operative pain and without significant adverse reactions for patients undergoing thyroid surgery.关键词
罗哌卡因/利多卡因/甲状腺手术/切口浸润/术后镇痛Key words
ropivacaine/lidocaine/thyroid surgery/incision infiltration/post-operative pain分类
医药卫生引用本文复制引用
王龙,杜健华,袁应川..罗哌卡因局部麻醉对甲状腺术后镇痛的临床观察[J].中国临床药理学杂志,2015,(5):333-335,3.基金项目
新疆医科大学创新基金资助项目 （）
