中国临床药理学杂志Issue(8)：618-620,634,4.DOI:10.13699/j.cnki.1001-6821.2015.08.011
谷氨酰胺强化肠外营养对全身炎症反应综合征患者影响的临床研究
Effect of glutamine on patients with systemic inflammatory response syndrome by strengthening parenteral nutrition
摘要
Abstract
Objective To explore the effect of glutamine on the nutritional status and inflammatory response by strengthening parenteral nutrition in patients after general surgery .Methods Forty patients with systemic inflammatory response syndrome ( SIRS ) in our hospital were selected , and all patients were randomly divided into treatment group and control group, with 20 cases in each group.Patients in treatment group were given glutamine to strengthen parenteral nutrition , while those in the control group received amino acid solution for parenteral nutrition .The treatment continued for one week .The data of level of hemoglobin , albu-min, transferrin and immunoglobulin (IgG, IgA, and IgM), as well as nutrition risk screening score and acute physiology , age and chronic health evaluation score in two groups before and after parenteral nutrition were recorded and compared .Results After parenteral nutrition , the data of hemoglobin ,albumin and transferrin in the treatment group were (116.5 ±9.2), (35.7 ±2.4) and (66.3 ±2.4) g・ L-1, respective-ly, and (102.5 ±8.6), (30.8 ±2.2) and (59.6 ±2.1) g・ L-1 in control group (P<0.05);after parenteral nutrition, the data of IgG, IgA, and IgM levels in the treatment group were significantly higher than those in the control group , and nutrition risk screening score and acute physiology and chronic health score were significantly lower than those in the control group (P <0.05).Conclusion The effect of glutamine parenteral nutrition on SIRS patients is significant , and it can im-prove patients′nutritional status and the immune function recovery .关键词
谷氨酰胺/肠外营养/营养状况/免疫功能Key words
glutamine/parenteral nutrition/nutritional status/immune function分类
医药卫生引用本文复制引用
王松志,吴乐军,吴应虬,朱建友..谷氨酰胺强化肠外营养对全身炎症反应综合征患者影响的临床研究[J].中国临床药理学杂志,2015,(8):618-620,634,4.基金项目
乐清市科技局基金资助项目 （）
